AntibodiesCULLIN Antibody

PDF

250489

0.1 mg

Brand

Abbiotec

Description

Cullin (Cullin-1, CUL1) is a core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cullin serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cullin contributes to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

Application

ELISAWB

Reactivity

HumanMouseRat

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