CYC116

Brand

No Brand

Description

CYC116 is a potent, small molecule inhibitor of Aurora A, B and C with IC50 value of 44, 19 and 65 nM respectively. Additionally, CYC116 is a potent inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2) kinase in vitro (IC50= 69 nM). CYC116 has antitumor activity in various solid tumor and leukemia xenograft model.

Application

Reactivity

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