Fibulin-5 Antibody

Brand

Abbiotec

Description

Fibulin-5 promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Fibulin-5 is a vascular ligand for integrin receptors and may play a role in vascular development and remodeling. Defects in fibulin-5 are a cause of autosomal dominant cutis laxa (ADCL). Hereditary cutis laxa refers to a heterogeneous group of connective tissue disorders characterized by cutaneous abnormalities and variable systemic manifestations. The most constant clinical feature is loose skin, sagging over the face and trunk.

Application

ELISAWB

Reactivity

BCanineHumanMouseRat

Photos