GDC-0879

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No Brand

Description

GDC-0879 is a potent and selective B-Raf kinase inhibitor with an EC50 of 0.75 µM. GDC-0879 has been used in various research studies for its anti-cancer properties. In GDC-0879-treated mice, both cell line- and patient-derived BRAFV600E tumors exhibited stronger and more sustained pharmacodynamic inhibition (>90% for 8 hours) and improved survival compared with mutant KRAS–expressing tumors.

Application

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