GLP-1 (A2) Antibody

Brand

Abbiotec

Description

Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody binds the free N-terminus of GLP-1 (7-37) and GLP-1 (7-36)amide and shows <0.2% cross-reactivity with GLP-1 (9-36)amide, glucagon and human GIP. The antibody cross-reacts 0.25% with GLP-1 (1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. Product Cat. No. 251101 is a biotin conjugate of Cat. No. 250244. Cat. No. 251101 can be used in a sandwich ELISA for detecting active GLP-1.

Application

Reactivity

Photos