AntibodiesGLP-1 (A2) Antibody

PDF

250244

0.2 mg

Brand

Abbiotec

Description

Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody binds the free N-terminus of GLP-1 (7-37) and GLP-1 (7-36)amide and shows <0.2% cross-reactivity with GLP-1 (9-36)amide, glucagon and human GIP. The antibody cross-reacts with Liraglutide, 0.25% with GLP-1 (1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. This antibody can be used in a sandwich ELISA for exendin-4.

Application

ELISA

Reactivity

Photos