Goat anti-ITM2B Antibody

ZZZZ_Status (Active, Disc) : Active

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

ITM2B; integral membrane protein 2B; ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; BRICHOS domain containing 2B; OTTHUMP00000018394

Antibody_Isotype
(Antibody only) :

Application_Details :

Western Blot: Approx. 30-35kDa band observed in HepG2 cell lysates (calculated MW of 30.3kDa according to NP_068839.1). Recommended concentration: 0.1-0.3µg/ml. Primary incubation 1 hour at room temperature. Preliminary testing was unsuccessful on Rat and Mouse Brain for this particular batch.Immunohistochemistry: Paraffin embedded Human Small Intestine. Recommended concentration: 2.5µg/ml.Immunofluorescence: Strong expression of the protein seen in the cytoplasm and Golgi apparatus of A431 and HeLa cells. Recommended concentration: 10µg/ml.

Flow Cytometry: Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/ml.

Peptide ELISA: antibody detection limit dilution 1:8000.

Background_Info :

Clone_Name
(AB only, monoclonals) :

Datasheet_Link :

Description (Long Description) : 

Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.

Expiry_Date : 

12 months after purchase if unopened.

Format (Form) : 

Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, C-HDKETYKLQRRETIK

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