Goat anti-PBR (mouse) Antibody

ZZZZ_Status (Active, Disc) : Active

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

PBR; Tspo; translocator protein; Bzrp; IBP; benzodiazepine receptor, peripheral; isoquinoline-binding protein; peripheral benzodiazepine receptor

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(Antibody only) :

Application_Details :

Western Blot: Approx.17kDa band observed in Mouse Kidney lysates and approx 16kDa iin lysates of cell line NIH3T3, and in preliminary testing of Rat Adrenal Gland lysate (calculated MW of 18.8kDa according to Mouse NP_033905.3). Recommended concentration: 0.01-0.1µg/ml. Primary incubation 1 hour at room temperature.Immunohistochemistry: Paraffin embedded Mouse Kidney. Recommended concentration: 10µg/ml.Flow Cytometry: Flow cytometric analysis of NIH3T3 cells. Recommended concentration: 10ug/ml.Peptide ELISA: antibody detection limit dilution 1:128000.

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(AB only, monoclonals) :

Datasheet_Link :

Description (Long Description) : 

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:9832438, PubMed:24814875), but its precise physiological role is controversial. According to some reports, it is not required for steroid hormone biosynthesis (PubMed:24174323, PubMed:24936060).

Expiry_Date : 

12 months after purchase if unopened.

Format (Form) : 

Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.

Immunogen (Antigen) :A synthetic peptide consisting of amino acids, C-RDNSGRRGGSRLPE

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