Human IL12A & IL27B Heterodimer Protein

Brand

Sino Biological

Description

IL12A is a subunit of a cytokine that acts on T and natural killer cells, and
has a broad array of biological activities. IL12A, together with IL27B, form a
disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the
T-cell-independent induction of interferon (IFN)-gamma, and is important
for the differentiation of both Th1 and Th2 cells. The responses of
lymphocytes to this cytokine are mediated by the activator of transcription
protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be
required for the signaling process of IL12A&IL27B in innate immunity.

Application

Reactivity

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