Human Noggin / NOG Protein (Fc Tag)

Species : Human

Synonyms : Noggin,SYM1,SYNS1

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE

Activity : 1. Measured by its ability to inhibit BMP2-induced alkaline phosphatase production by MC3T3-E1 cells.
The ED50 for this effect is typically 1.5-2.0 £gg /mL in the presence of 0.25-0.5 £gg/mL of BMP-2.
2. Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3-E1 cells.
The ED50 for this effect is typically 0.1-0.6 £gg/mL in the presence of 50 ng/mL of hBMP4.