Influenza A [A/Hong Kong/483/97 (H5N1)] Hemagglutinin (HA) Protein, His Tag

Source : 

Influenza A [A/Hong Kong/483/97 (H5N1)] HA, His Tag (HA1-V5229) is expressed from human 293 cells (HEK293). It contains AA Asp 17 – Gln 531 (Accession # AAC32099.1).

Molecule : Hemagglutinin (HA)

Synonyms : HA,Hemagglutinin

Format : Powder

Category : Viral Proteins

Accession : N/A

Storage : -20℃

Shipping condition : Powder,RT

Molecular Weight : 60.1 kDa

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 66-100 kDa under reducing (R) condition (SDS-PAGE).

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

Buffer : PBS, pH7.4

Description :

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

References :

(1) Suarez D.L.,et al., 1998, J. Virol. 72:6678-6688