Influenza A [A/Thailand/1(KAN-1)/2004 (H5N1)] Neuraminidase (NA) Protein, His Tag
H54-V5247
100ug
Brand
ACROBiosystems
Description
Source :
Influenza A [A/Thailand/1(KAN-1)/2004 (H5N1)] NA, His Tag (H54-V5247) is expressed from human 293 cells (HEK293). It contains AA His 36 – Lys 449 (Accession # H8PF47).
Molecule : Neuraminidase (NA)
Synonyms : NA,Neuraminidase
Format : Powder
Category : Viral Proteins
Accession : N/A
Storage : -20℃
Shipping condition : Powder,RT
Molecular Weight : 46.1 kDa
Characteristics :
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.1 kDa. The protein migrates as 50-57 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level : Less than 1.0 EU per μg by the LAL method.
Buffer : PBS, pH7.4
Description :
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
References :
(1) Manz B., et al., 2012, Submitted to the EMBL/GenBank/DDBJ databases.
Application
Reactivity