AntibodiesINSR Antibody

PDF

200110

0.1 mg

Brand

Abbiotec

Description

INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3′-kinase (PI3K). Defects in INSR are the cause of insulin resistance.

Application

ELISA

Reactivity

HumanMouse

Photos

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