Ivermectin B1a; Dihydroavermectin B1a; CAS 70288-86-7
(Antibody only) :
Positive allosteric modulator of the alpha-7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM).
Pharmacology: A specific inhibitor of importin alpha/beta-mediated nuclear import with no effect on a range of other nuclear import pathways (1). Displays potent antiviral activity against HIV-1, dengue (1), corona (2) and other viruses. Clinically useful broad-spectrum antiparasitic agent (3). PubChem CID: 6321424.
Product is sold for research use only. Not for human therapeutic use or for medicinal purposes.
Store desiccated as supplied at -20C for up to 2 years. Store solutions at -20C for up to 1 month. Prevent multiple freeze-thaw cycles.