LINGO1 Antibody

Brand

Abbiotec

Description

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO1) is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also a negative regulator of oligodentrocyte differentiation and axonal myelination. LINGO1 acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.

Application

ELISAIHCIP

Reactivity

ChickenHumanMouse

Photos