Lofexidine hydrochloride

Brand

No Brand

Description

Lofexidine hydrochloride is an α2A-AR (adrenoceptor) agonist that is structurally related to Clonidine and used in the treatment of opioid withdrawal symptoms as well as an anihypertensive. Lofexidine inhibits the release of norepinephrine in the central and peripheral nervous system, thereby reducing some of the withdrawal symptoms, but it has no documented effect on drug craving and endogenous opioid levels.

Application

Reactivity

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