AntibodiesMouse monoclonal antibody to human LIMK-1 [1A8]: IgG

PDF

M-844-100

100 µg

Brand

biosensis

Description

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

LIM domain kinase 1; LIMK1; LIMK

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

This antibody is recommended for WB, IHC and sandwich ELISA. For IHC, a concentration of 3 µg/mL is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : 1A8

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=400

 

Description (Long Description) : 

LIMK-1  belongs to a small subfamily of LIM proteins with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 regulates actin filament dynamics. It phoshorylates and inactivates the actin binding/ depolymerising factor cofilin, consequently stabilising the actin cytoskeleton. It may also be involved in brain development. LIMK-1 localises to the cytoplasm and is highly expressed in both the adult and fetal nervous system. It is expressed to a lesser extent in heart and skeletal muscle. LIMK-1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
 

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized from PBS pH 7.2

 

Immunogen (Antigen) :Partial recombinant protein of human LIMK-1 (aa 548 to 648) with a GST tag.

 

Kit_Components :

 

MSDS (File name) :

 

Application

ELISAWB

Reactivity

Human

Photos

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