Nafamostat Mesylate
S1386
10mM/1mL~500mg
Brand
Selleckchem
Description
Nafamostat Mesylate
Catalog No.S1386
Nafamostat Mesylate is an anticoagulant.Phase 4.
Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
Nafamostat is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. [1]
Clinical Trial Information( data from http://clinicaltrials.gov)
| NCT Number | Recruitment | Conditions | Sponsor /Collaborators |
Start Date | Phases |
|---|---|---|---|---|---|
| NCT01761994 | Completed | Acute Kidney Injury | Yonsei University|SK Chemicals Co.,Ltd. | 2007-09 | Phase 4 |
| NCT01001403 | Completed | Liver Transplantation|Postreperfusion Syndrome | Seoul National University Hospital | 2009-03 | Phase 4 |
| NCT01486485 | Recruiting | Acute Kidney Injury | Seoul National University Hospital|SK Chemicals Co.,Ltd. | 2012-03 | Phase 3 |
Chemical Information
Download Nafamostat Mesylate SDF
| Molecular Weight (MW) | 539.58 |
|---|---|
| Formula |
C19H17N5O2.2CH4O3S |
| CAS No. | 82956-11-4 |
| Storage | 3 years -20℃Powder |
|---|---|
| 6 months-80℃in DMSO | |
| Syonnyms | Futhan, FUT-175 |
| Solubility (25°C) * | In vitro | DMSO | 20 mg/mL (37 mM) |
|---|---|---|---|
| Water | 53 mg/mL (98 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Chemical Name | 6-carbamimidoylnaphthalen-2-yl 4-guanidinobenzoate dimethanesulfonate |
|---|
Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
|---|---|---|---|---|
| Mass(mg) | 0.53958 | 5.3958 | 10.7916 | 16.1874 |
Application
Reactivity
