Osterix Antibody

Brand

Abbiotec

Description

Transcription factor Sp7 (osterix) is a transcriptional activator essential for osteoblast differentiation. Osterix binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences. Defects in osterix are the cause of osteogenesis imperfecta type 11 (OI11). OI11 is a connective tissue disorder characterized by bone fragility, low bone mass, recurrent fractures, mild bone deformations, generalized osteoporosis, delayed teeth eruption, no dentinogenesis imperfecta, normal hearing, and white sclerae.

Application

ELISAIHCWB

Reactivity

HumanMouse

Photos