Oxymetazoline HCl
S2495
10mM/1mLã€50mg
Brand
Selleckchem
Description
Oxymetazoline HCl
Oxymetazoline HCl is an α1 and α2 adrenergic receptor agonist.
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Biological Activity
Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist. It is available over-the-counter as a topical decongestant in nasal sprays. The action of oxymetazoline results in vasoconstriction. In addition, the local application of the drug also results in vasoconstriction due to its action on endothelial postsynaptic α2 receptors; systemic application of α2 agonists, in contrast, causes vasodilation because of centrally-mediated inhibition of sympathetic tone via presynaptic α2 receptors. [1]
Chemical Information
Download Oxymetazoline HCl SDF
| Molecular Weight (MW) | 296.84 |
|---|---|
| Formula |
C16H24N2O.HCl |
| CAS No. | 2315-02-8 |
| Storage | 3 years -20℃Powder |
|---|---|
| 6 months-80℃in DMSO | |
| Syonnyms | N/A |
| Solubility (25°C) * | In vitro | DMSO | 59 mg/mL (198 mM) |
|---|---|---|---|
| Water | 59 mg/mL (198 mM) | ||
| Ethanol | 59 mg/mL (198 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
|---|---|---|---|---|
| Mass(mg) | 0.29684 | 2.9684 | 5.9368 | 8.9052 |
Application
Reactivity
