Rabbit antibody to human methyl-CpG binding protein 2 (MeCP2), (471-486): Affinity purified

ZZZZ_Status (Active, Disc) : Active

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

CNPase

Antibody_Isotype
(Antibody only) :

Application_Details :

Western blotting (1:1,000-1:5,000) and Immunohistochemistry (1:1,000) Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Background_Info :

Clone_Name
(AB only, monoclonals) :

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1638

Description (Long Description) : 

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org

Expiry_Date : 

12 months after purchase if unopened.

Format (Form) : 

Lyophilized from a solution containing PBS buffer pH 7.2-7.6 with 3% trehalose, without preservatives.

Immunogen (Antigen) :A synthetic peptide (REEPVDSRTPVTERVS, aa: 471-486) of C-terminus of human protein.

Kit_Components :

MSDS (File name) :