Rabbit polyclonal antibody to human NOGO-A (1170-1192): Affinity purified

ZZZZ_Status (Active, Disc) : Discontinued

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

RTN 4A; Nogo-A; RTN-xL; Reticulon-4; Neurite outgrowth inhibitor; Foocen; NSP;

Antibody_Isotype
(Antibody only) :

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Background_Info :

Clone_Name
(AB only, monoclonals) :

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1207

Description (Long Description) : 

Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle.

Expiry_Date : 

12 months after purchase

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

Immunogen (Antigen) :A synthetic peptide corresponding to a region (1170-1192) from the C-terminus of human NOGO-A.

Kit_Components :

MSDS (File name) :