Rabbit polyclonal antibody to N-methyl-D-aspartate receptor 1 (36-53): Affinity purified

ZZZZ_Status (Active, Disc) : Active

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; N-methyl-D-aspartate receptor; Grin1; Nmdar1;

Antibody_Isotype
(Antibody only) :

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Rat NMDAR1 (isoform A) has a predicted length of 938 residues and molecular weight of 106 kDa. A concentration of 0.5-1 µg/mL is recommended to detect NMDAR1 in paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Background_Info :

Clone_Name
(AB only, monoclonals) :

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1568

Description (Long Description) : 

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channels are formed from heteromers composed of three different subunits: the key receptor zeta subunit NMDAR1 (GRIN1) with an NMDAR2 epsilon subunit: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), or NMDAR2D (GRIN2D) and a third subunit: GRIN3A or GRIN3B. At least 7 isoforms of NMDAR1 are produced by alternative splicing.

Expiry_Date : 

12 months after purchase

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

Immunogen (Antigen) :A synthetic peptide corresponding to a sequence at the N-terminus of human NMDAR1 (36-53aa RKHEQMFREAVNQANKRH), identical to the related rat and mouse sequences.

Kit_Components :

MSDS (File name) :