Rabbit Serum Albumin Protein, His Tag

Source : 

Rabbit Serum Albumin, His Tag (RSA-R52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 25 – Gly 608 (Accession # P49065-1).

Molecule : Serum Albumin

Synonyms : Serum albumin,ALB,Alb

Format : Powder

Category : Other Recombinant Proteins

Accession : NP_001075813.1

Storage : -20℃

Shipping condition : Powder,RT

Molecular Weight : 67.9 kDa

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.9 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE).

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

Buffer : PBS, pH7.4

Description :

serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

References :

(1) Carter D.C., et al., 1989, Science 244:1195-1198.
(2) Minchiotti L., et al., Eur. 2001, J. Biochem. 268:344-352.
(3) Minchiotti L., et al., 1992, Biochim. Biophys. Acta 1119:232-238.