RGD-4C Peptide

Brand

Abbiotec

Description

The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD-4C is a double cyclic peptide that can bind preferentially to integrins at sites of tumor angiogenesis and inflamed synovium in vivo, and can be internalized into targeted cells. Recent applications include RGD-4C coupling to proapoptotic domains to treat tumors and inflammatory arthritis, or to radioactive labels for the broad spectrum imaging of tumor tissue.

Application

Reactivity

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