RUNX2 Antibody

Brand

Abbiotec

Description

Runt-related transcription factor 2 (RUNX2) is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 is essential for the maturation of osteoblasts. Defects in RUNX2 are the cause of cleidocranial dysplasia (CLCD), also known as cleidocranial dysostosis (CCD). CLCD is an autosomal dominant skeletal disorder with high penetrance and variable expressivity.

Application

ELISAIHC

Reactivity

HumanMouse

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