TCF3 (6B8) Antibody

Brand

Abbiotec

Description

TCF3 (Transcription factor 3) is a transcriptional regulator, involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5′-CANNTG-3′. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

Application

WB

Reactivity

Photos