Trop-2 Antibody

Brand

Abbiotec

Description

TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. (Trop-2) is necessary for tumorigenesis and invasiveness of colon cancer cells, as both are inhibited when Trop-2 expression is suppressed by RNA interference. Defects in trop-2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.

Application

ELISAIHC

Reactivity

HumanMouse

Photos