UbcH8

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E2-644

50 μg 100 μg

Brand

Boston Biochem

Description

UbcH8

Catalog #: E2-644

UbcH8
Product Source: 

human recombinant

UbcH8 can be charged with both ubiquitin and ISG15 via the activities of the respective E1Ub and E1ISG15 enzymes. UbcH8 is highly homologous to UbcH7, and functions in ubiquitin conjugation reactions and in HECT E3 (such as E6-AP) and RING-FINGER (such as Parkin) protein mediated events. UbcH8 is the major E2 for ISG15 conjugation in reactions initiated by the ISG15-specific E1 activating enzyme. ISG15 is an ubiquitin-like protein that is conjugated to cellular proteins after IFN-α/β stimulation.

Product Information
Quantity: 

50 μg 100 μg

Stock: 

X mg/ml (XμM) in 50 mM HEPES pH 8.0, 100 mM NaCl,10% glycerol. Actual concentration will vary with specific lot number.

MW: 

18 kDa

Purity: 

> 95% by SDS-PAGE

 

Use & Storage
Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.

Application

Reactivity

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