UM729
HY-15972
10 mM * 1 mL in DMSO，5 mg，10 mg，50 mg，100 mg，200 mg，500 mg
Brand
MCE
Description
UM729 is a new pyrimidoindole, which has an additive effect with AhR antagonists in preventing differentiation in most AML specimens; collaborates with Ahr suppressors in preventing AML cell differentiation. IC50 value: Target: SR1 and UM729 can be implemented as a standardized supplement in culture media and will pave the way for studies of self-renewal mechanisms and for the identification of new antileukemic drugs through cell-based assays for primary human AML cells.
Application
Reactivity
