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Online View
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Mutations in the Spike Glycoprotein of Omicron
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The Omicron variant is by far the most divergent variant characterized by a high number of mutations in the spike protein. Several mutations (e.g., N501Y, P681H) have been identified in previous variants and are associated with increased transmissibility, immune escape, or other properties.
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• 30 amino acid changes: among which 15 are located in the RBD region
• Three deletions
• Three insertions in the spike protein NTD
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Sino Biological is developing a series of recombinant Omicron Spike Proteins to support the study of Omicron variant.
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Please contact us for more detailed information.
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Cat#
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Molecules
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Host
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Tag
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Mutants
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40592-V08H121
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RBD
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HEK293
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C-His
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G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H
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40592-V49H7
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RBD
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HEK293
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C-His-AVI
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G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H
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40592-V49H7-B
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RBD
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HEK293
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C-His-AVI
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G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H
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40591-V08H41
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S1
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HEK293
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C-His
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A67V, H69del, V70del, T95I, G142D, V143del, Y144del, Y145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H
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40589-V08H26
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S-ECD Trimer
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HEK293
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C-His
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A67V, H69del, V70del, T95I, G142D, V143del, Y144del, Y145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
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40589-V49H3-B
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S-ECD Trimer
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HEK293
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C-His-AVI
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A67V, H69del, V70del, T95I, G142D, V143del, Y144del, Y145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
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40589-V08B33
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S-ECD
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Insect
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C-His
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A67V, H69del, V70del, T95I, G142D, V143del, Y144del, Y145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
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40588-V07E34
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N
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E.coli
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N-His
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P13L, E31del, R32del, S33del, R203K, G204R
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