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亞旭代理的Sino Biological可以為科研單位、生物技術和製藥公司提供最專業的抗體生產服務,從抗原基因合成到最後抗體生產一站式完整的服務皆能提供。 |
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多樣的抗體開發技術
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Mouse mAb Development
(Hybridoma)
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Single B-cell Based Platform
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Rabbit mAb Development
(Phage Display)
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Rabbit pAb Development
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服務優勢
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免費 免費提供抗原評估和動物免疫設計
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快速 優化免疫條件(小鼠/兔子):最快 5 週即可獲得抗體!
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彈性 依照客戶需求可以獲得所需要的clone數
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綜合 依照所需可提供包裝服務(重組抗體生產)
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多種抗體開發服務
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服務案例分享
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Case #1: Anti-idiotype mAb Generation
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Sino Biological has successfully completed several anti-ID development projects that recognize BsAb drugs.
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Seven anti-idiotype mouse monoclonal antibody clones showed highly specific binding to the BsAb drug, and exhibited no binding to human IgG isotype control or total human IgG.
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Case #2: Bispecific Antibody Production
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Starting from the antibody sequence, Sino Biological can deliver multiple bsAb formats such as BiTE, Diabody, CrossMab and DVD-IgG. The company has completed many bsAb production projects with >90% of overall success rates, and the highest yield has even reached ~250mg/L.
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Protein A-Affinity
SDS-PAGE>95%; Monomer: 68.5%
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Ion Exchange
SDS-PAGE>95%; Monomer: 83%
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Gel Filtration
SDS-PAGE>95%; Monomer: 96.6%
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After the three-step purification process, monomer purity was changed from 68.5% to 96.6%, meeting the final QC requirements.
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The Three-Step Process to Purify BsAbs
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