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Seasonal flu (influenza) is a common infectious disease of the respiratory tract causing mild to severe illness. Vaccination is the most effective way to prevent seasonal flu. Each year, 3-4 different flu strains will be selected as vaccine strains based on surveillance data of the recent isolates, and the performance of the vaccines from the previous season.
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The annual vaccine strains normally include both influenza A and influenza B. There are many subtypes of influenza A based on the subtype of two surface antigens, hemagglutinin (HA) and neuraminidase (NA), while influenza B is divided into two lineages, the Yamagata lineage, and the Victoria lineage.
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To support influenza research, Sino Biological has developed a panel of recombinant antigen products covering most of the vaccine strains from 2015-2020. The products include both HA and NA proteins, and some nucleoprotein (NP) proteins. Customized production is available if your antigen (or strain) of interest is not on the current list.
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Year 2020 ~ 2021
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A/Guangdong-Maonan/SWL1536/2019 (H1N1)
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Egg-based (quadrivalent, trivalent)
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HA: 40717-V08H
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NP: 40723-V08B
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A/Hawaii/70/2019 (H1N1)
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Cell- or recombinant-based (quadrivalent, trivalent)
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HA: 40717-V08H
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NP: 40724-V08B
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A/Hong Kong/45/2019 (H3N2)
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Cell- or recombinant-based (quadrivalent, trivalent)
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HA: 40765-V08H (Under Development)
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NP: 40754-V08B
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B/Washington/02/2019
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Egg-based, Cell- or recombinant-base (quadrivalent, trivalent)
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HA: 40722-V08H
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NP: 40755-V08B
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Year 2019 ~ 2020
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A/Brisbane/02/2018 (H1N1)
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Egg-based (quadrivalent)
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HA: 40719-V08H
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A/Kansas/14/2017 (H3N2)
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Egg-based (quadrivalent)
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HA: 40720-V08H
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B/Colorado/06/2017
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Egg-based (quadrivalent); trivalent
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HA: 40581-V08H
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Year 2018 ~ 2019
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A/Singapore/INFIMH-16-0019/2016 (H3N2)
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quadrivalent
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HA: 40580-V08H
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B/Colorado/06/2017
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quadrivalent; trivalent
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HA: 40581-V08H
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Year 2017 ~ 2018
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Year 2016 ~ 2017
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Year 2015 ~ 2016
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