Sino Biological | 神經細胞培養的神經營養因子

Sino Biological | 神經細胞培養的神經營養因子

2022.12.07

 

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神經營養因子Neurotrophic Factors(NTF) 控制神經細胞增殖和分化,這些因子在損傷後促進細胞存活和再生的能力,尤其是在中風和腦損傷後,因此常被應用於神經細胞培養和分化研究。此外NTF是作為治療性生物製劑在中樞神經系統Central Nervous System(CNS) 中測試的首批因子。
NTF 的梯度濃度: NGF, NT-3, GDNF, 和 BDNF 顯示神經細胞生長。除了NTF,NT-4, CDNF, MANF, NT-5, PDGF, LIF, Midkine和NFT受體(TrkA, TrkB, TrkC) 正在進行臨床前和臨床研究,並且有好的結果。
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重組NTF蛋白
Human NGF Protein | 11050-HNAC
Cell proliferation assay using TF-1 human erythroleukemic cells
Human GDNF Protein | 10561-HNCH
Binding ability by ELISA. Immobilized human GFRA1 (Cat#:10330-H02H) can bind GDNF
Human TrkA Protein | 11073-H03H
Ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells
Human TrkC Protein | 10048-H08H
Immobilized human TrkC can bind biotinylated human NT3 (Cat#:10286-HNAE)
• 更多相關蛋白
GFRa RET IL-6 IGF-1 EGF CNTF
TGF-alpha TGF-beta VEGF FGF BMP IL-2
IL-3 IL-5 PKC Akt MAPK

 

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