Sino Biological | 優質抗體生產服務

Sino Biological | 優質抗體生產服務

2022.04.11

 

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Sino Biological

 

Antibody Development Expert

CRO服務

抗體開發與生產服務

蛋白表達服務

亞旭代理的Sino Biological可以為科研單位、生物技術和製藥公司提供最專業的抗體生產服務,從抗原基因合成到最後抗體生產一站式完整的服務皆能提供。

多樣的抗體開發技術

Mouse mAb Development
(Hybridoma)

Single B-cell Based Platform

Rabbit mAb Development
(Phage Display)

Rabbit pAb Development

 

服務優勢

免費  免費提供抗原評估和動物免疫設計

 

快速  優化免疫條件(小鼠/兔子):最快 5 週即可獲得抗體!

 

彈性  依照客戶需求可以獲得所需要的clone數

 

綜合   依照所需可提供包裝服務(重組抗體生產)

 

多種抗體開發服務

Fast Mouse mAb Development

Fast Rabbit pAb Production

Rabbit mAb Development

Single B Cell Antibody Service

Phospho-Specific Antibody Services

Small to Mid-scale Antibody Production Service

Chimeric Antibody Production Service

Bispecific Antibody Production Service

 

Standard Mouse mAb Development

Standard Rabbit pAb Production

Antibody Humanization Service

Anti-idiotype Antibody Services

High-throughput Antibody Production Service

Large-scale Antibody Production Service

Antibody Fragment Production Service

 

服務案例分享

Case #1: Anti-idiotype mAb Generation

Sino Biological has successfully completed several anti-ID development projects that recognize BsAb drugs.

Seven anti-idiotype mouse monoclonal antibody clones showed highly specific binding to the BsAb drug, and exhibited no binding to human IgG isotype control or total human IgG.

Case #2: Bispecific Antibody Production

Starting from the antibody sequence, Sino Biological can deliver multiple bsAb formats such as BiTE, Diabody, CrossMab and DVD-IgG. The company has completed many bsAb production projects with >90% of overall success rates, and the highest yield has even reached ~250mg/L.

Protein A-Affinity
SDS-PAGE>95%; Monomer: 68.5%

Ion Exchange
SDS-PAGE>95%; Monomer: 83%

 

Gel Filtration
SDS-PAGE>95%; Monomer: 96.6%

After the three-step purification process, monomer purity was changed from 68.5% to 96.6%, meeting the final QC requirements.

The Three-Step Process to Purify BsAbs

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