Project
Type |
De novo Ab design |
Ab Affinity maturation
(fixed template) |
| Customer Input |
• Ag sequences (required)
• Any positive or negative Ab sequences (preferred) |
• Ag sequence (required)
• Ab template sequence (required)
• Any positive or negative Ab sequences (preferred)
• Binding affinity data (preferred) |
| Description |
• The entire antigen will be assessed for possible epitopes
• Existing data from clients might be needed to build a customized AI model. |
• If an Ab template is to be preserved across all mutant candidate Abs, mutagenesis will only be performed on the CDR regions of VH and VL.
• The binding epitope remains the same across all candidate Abs. |
| Deliverable |
20-100 ranked antibody sequences | Purified Antibodies | Project report |
| Timeline |
4-6 weeks |
