|
|
|
Antibody Fragments 不僅保留完整單株抗體的專一性,並且還適用於一系列治療和診斷應用的優異特性。 由於其尺寸小,Antibody Fragments 可增強在組織的滲透性、結合傳統上難以接近的抗原表位的能力,並降低免疫原性。 此外片段提供結構靈活性、易於生產和基因工程設計,並可作為新型結構。 Sino Biological 在多種抗體片段的生產和純化方面擁有豐富的經驗,包括 單價形式 (如: Fab、scFv 和 VHH) 和 雙特異性結構 (如: BiTE and Diabody). |
|
|
|
|
Sino Biological Antibody Fragments 生產服務亮點 |
|
Years of Experience in Antibody Production |
|
|
Multiple Expression Systems
HEK293, CHO, and cell-free system |
|
|
High-throughput Platform
• 1,000+ antibodies per batch
• Fast delivery: as quickly as 2 WEEKS
• Proprietary mammalian expression platform
Click |
|
|
Cell-free Synthesis
• Antibody expression in HOURS
• Purified antibody in 1 DAY
• Success rate >99%
Click |
|
|
|
|
Case Studies |
1 CD3×BCMA BiTE Expressed by HEK293 |
Purity >95%
By SDS-PAGE and SEC-HPLC
|
CD3 and BCMA Binding Activity
EC50 = 6.7 ng/mL
|
2 VHH and scFv Synthesized by Cell-free System |
High-purity VHH Synthesis |
High-throughput scFv Synthesis |
Purity >95%
By SDS-PAGE and SEC-HPLC
|
Only 5 Days:
From Gene Synthesis to 50 Purified scFvs
|
|
|
Related Services |
|
|
|
|