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| The Global Leader in Recombinant Technology |
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SuperNuclease® Pro:
Conquers Hard-to-Degrade
Nucleic Acids
 Ends Oct 31, 2026 | Claim Your Free Trial >>>
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| Drug regulatory authorities in various countries have set strict limits on residual nucleic acids in biological products. Efficient removal of residual nucleic acids during production is crucial to ensure compliance with regulatory standards. SuperNuclease® Pro (Cat#: SSNP02) is our next-generation, highly purified nuclease engineered for demanding bioprocessing workflows. Building on our foundational SuperNuclease®, this optimized version delivers significantly higher catalytic activity than wild-type Serratia marcescens nuclease across diverse cell culture and virus harvest conditions, providing enhanced performance for efficient nucleic acid removal in bioprocessing applications. |
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| Product Advantages |
| More Effective Removal of Hard-to-hydrolyze Nucleic Acids |
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Higher Activity in Cell Culture & Virus Harvest Conditions |
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| Broader Adaptability to Physiological Salt Conditions |
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Greater Thermostability for Consistent, Premium Performance |
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| Higher Nucleic Acid Removal Efficiency vs. Competitors |
| The figure below compares the host nucleic acid removal efficiency of Sino Biological’s SuperNuclease® Pro (Cat#: SSNP02) with that of competitor nucleases, demonstrating that SN Pro significantly outperforms the competitors in degradation performance. |
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| Validated Activity and Real-time Thermo-stability |
| Activity Validation |
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| SuperNuclease® Pro (Cat#: SSNP02) maintains high activity across a broad range of NaCl concentrations, pH, temperatures, and Mg²⁺ conditions. |
| Thermo-stability (Real-time) |
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| SuperNuclease® Pro (Cat#: SSNP02) demonstrates excellent stability, confirmed by 180-day real-time validation at 37°C. |
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