SinoBiological | 認識呼吸道融合病毒 (RSV),推動 RSV Pre-F 疫苗市場

SinoBiological | 認識呼吸道融合病毒 (RSV),推動 RSV Pre-F 疫苗市場

2024.09.22

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9-1 RSV Pre-F Protein

SignalChem Kinase
(Part of Sino Biological)

Comprehensive Solutions

Featured Products

Recombinant Production
(C4B US-based Center)

Respiratory Syncytial Virus (RSV) is a significant public health concern, particularly for infants, young children, and older adults, causing severe respiratory diseases. Recently, the FDA approved vaccines Abrysvo and Arexvy, which utilize the stable prefusion F (pre-F) protein to enhance immunity and effectively protect against RSV. Sino Biological provides a comprehensive collection of recombinant antigens and antibodies, including the RSV pre-F antigen, to advance the development of vaccines, therapeutic antibodies, and diagnostic assays.

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Featured RSV Pre-F/Post-F Proteins

 


Validated by conformation-specific antibodies


Trimer purity validated by SEC-MALS


CHO/KEK293 expression

 

 

 

Human RSVA Pre-F Protein

Human RSVB Post-F Protein (His Tag)

Cat#: 11049-VNAS

Cat#: 40999-V08H

RSV-preF can bind antibody which targets antigenic Site V, the EC50 is 0.05-0.15 ng/mL (Routinely tested).

RSVB post-F can bind Anti-Fusion F0 Antibody 1 (site II), the EC50 is 10-30 ng/mL and not bind Anti-Fusion glycoprotein F0 Antibody 2 (Site Ø).

 

More RSV Proteins

Molecule

Cat#

Strain

Tag

Expression Host

Purity

Pre-F

11049-V49H-B

A2

C-His-AVI

HEK293 Cells

≥ 90%

Pre-F

11049-VNAS-B

A2

no tag

CHO Stable Cells

≥ 90%

Pre-F

40999-VNAS

RSVB

no tag

CHO Stable Cells

≥ 95%

Post-F

11049-V08H5

A2

C-His

HEK293 Cells

≥ 95%

Explore More RSV Antigens and Antibodies 

Learn More about Respiratory Viruses

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Sino Biological

Sino Biological US Inc. (U.S.A.)

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Sino Biological Europe GmbH (Europe)

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Sino Biological, Inc. (China)

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株式会社日本シノバイオロジカル (Japan)

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