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The RAS/RAF/MAPK pathway, essential for cell processes like proliferation and survival, is a key target for treating cancer, RASopathies, and inflammatory conditions. Key components include RAS proteins (HRAS, KRAS, and NRAS), RAF proteins (ARAF, BRAF, and CRAF), MEK kinases, and ERK kinases. Other MAPK pathways include the p38 signaling pathway, the JNK pathway, the ERK5 pathway, and more. With SignalChem Biotech now part of Sino Biological, we can offer an expanded range of recombinant enzymes, validated antibodies, qPCR primers, and cell lysates to support research on MAPK pathways for cancer and other diseases.
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