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Online View
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Tau proteins are essential for stabilizing neuronal microtubules, but their abnormal phosphorylation in Alzheimer’s disease (AD) contributes significantly to neurodegenerative processes. Recent research has underscored the importance of tau proteins. In fact, phosphorylated tau proteins are established to be better indicators of disease progression and neurofibrillary pathology compared to amyloid-β plaques. SignalChem Biotech, now part of Sino Biological, provides an extensive range of premium recombinant tau proteins, including Tau-441 and its variants, as well as phosphorylated tau proteins to support research into tau phosphorylation and its implications in neurodegenerative diseases.
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SignalChem Tau Competitive Advantages
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Native Conformations
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• Nearly all of our Tau products are tag-free
• Proteins mimic their native conformation and biological activity
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Flexibility in Assays
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• Tag-free Tau proteins offer flexibility in experimental design and assay development
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Clinical Relevance
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• Native Conformations and assays flexibility provide stronger clinical relevance when
evaluating potential therapeutic interventions
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Learn More about SignalChem Tau Proteins 
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Featured Tau Proteins
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Tau-411, GSK3beta-phosphorylated
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(Cat#: T08-50FN)
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The purity of Tau441, GSK3β-phosphorylated was determined to be >90% by densitometry, approx. MW 64~68 kDa.
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Tau-411, Biotinylated
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(Cat#: T08-54B2N)
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The purity of biotinylated Tau-441 was determined to be >90% by densitometry.
Observed MW ~64 kDa. Calculated MW 45.9 kDa.
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More Tau Proteins
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Product
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Cat#
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Species
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Tag
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Expression Host
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Sequence
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Tau-441 (244-372)
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T08-55N
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Human
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Tag-free
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E.coli
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244-372
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Tau-441
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T08-54H
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Human
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His
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E.coli
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Full length
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Tau-441,
DYRK1A-phosphorylated
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T08-50RN
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Human
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Tag-free
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E.coli
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Full length
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View All Tau Proteins
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September is World Alzheimer’s Month
World Alzheimer’s Month, observed every September, aims to raise awareness about Alzheimer’s disease and dementia. It emphasizes that dementia is not a normal part of aging and encourages communities to take action. Activities include educational events, fundraising, and sharing information to combat stigma. World Alzheimer’s Day, on September 21st, is a key highlight, focusing global attention on the challenges faced by those affected by dementia.
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