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Tau proteins play a key role in studying neurodegenerative diseases like Alzheimer’s, where abnormal phosphorylation leads to neurofibrillary tangles and cognitive decline. SignalChem Biotech – now part of Sino Biological – has developed the world’s largest portfolio of recombinant Tau proteins, including diverse isoforms and phosphorylation states, which have been instrumental in biomarker detection and research on tauopathies. These products have supported studies on Tau’s impact on neuronal function and injury models, highlighting SignalChem’s commitment to advancing therapeutic development and understanding Tau-related disease mechanisms.
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Click to View Advances in Targeting Tau Proteins 
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World’s Largest Portfolio of Recombinant Tau Proteins
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Diverse Tau Isoforms and
Phosphorylation States Available
e.g., Phosphorylated Tau 217 and 181
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Highly Cited
in Reputable Journals
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Various Kinase Phosphorylated Tau Proteins
e.g., GSK3β, DYRK1A, PHKG2, PKA, TTBK1,
BRSK1, or CAMK2-phosphorylated Tau
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Nearly All of Our Tau Proteins Are Tag-Free
Mimicking native conformations and offering
flexibility in assays
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Many Different Tau Mutations
e.g., K257T, L266V, G272V, N279K, ΔK280, ΔN296, P301S, P301L, V337M, and R406W
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Learn More about Highly Cited Tau Proteins
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Featured Full-Length Human Tau Proteins
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Tau-441 Protein
Tag-Free
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22 Citations
Cat#: T08-54N
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The purity of Tau-441 (4μg) was determined to be ~70% by densitometry.
Observed MW ~64 kDa.
Calculated MW 45.9 kDa.
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Tau-441 Protein
Biotinylated
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3 Citations
Cat#: T08-54BN
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The purity of biotinylated Tau-441 was determined to be >80% by densitometry.
Observed MW ~64 kDa.
Calculated MW 45.9 kDa.
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Tau-441 Protein, Tag-Free
GSK3β-Phosphorylated
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5 Citations
Cat#: T08-50FN
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The purity of Tau-441, GSK3β-phosphorylated was determined to be >90% by densitometry.
Approx. MW 64~68 kDa.
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Click to View All Recombinant Tau Proteins
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View Tau Poster
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• Physiological and pathological roles of Tau proteins
• Advances in targeting Tau proteins in neurodegenerative diseases
• Tau proteins used and cited in high impact journals
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View Poster Now
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Don’t Miss Out!
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Kinase Drug Discovery Solutions >> |
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Center for Bioprocessing (C4B)
US-Based Recombinant Production >>
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